Major Interaction Do not take this combination

  • Warfarin (Coumadin) interacts with GLUCOSAMINE SULFATE
    Warfarin (Coumadin) is used to slow blood clotting. There are several reports showing that taking glucosamine with or without chondroitin increase the effect of warfarin (Coumadin) on blood clotting. This can cause bruising and bleeding that can be serious. Don’t take glucosamine if you are taking warfarin (Coumadin).

Moderate Interaction Be cautious with this combination

  • Medications for cancer (Antimitotic chemotherapy) interacts with GLUCOSAMINE SULFATESome medications for cancer work by decreasing how fast cancer cells can copy themselves. Some scientists think that glucosamine might increase how fast tumor cells can copy themselves. Taking glucosamine along with some medications for cancer might decrease the effectiveness of these medications for cancer.
    Some of these medications are etoposide (VP16, VePesid), teniposide (VM26), and doxorubicin (Adriamycin).

Minor Interaction Be watchful with this combination

  • Acetaminophen (Tylenol, others) interacts with GLUCOSAMINE SULFATE
    There is some concern that taking glucosamine sulfate and acetaminophen (Tylenol, others) together might affect how well each works. But more information is needed to know if this interaction is a big concern.
  • Medications for diabetes (Antidiabetes drugs) interacts with GLUCOSAMINE SULFATEThere has been concern that glucosamine sulfate might increase blood sugar in people with diabetes. There was also the concern that glucosamine sulfate might decrease how well medications used for diabetes work. However, research now indicates that glucosamine sulfate probably does not increase blood sugar in people with diabetes. Therefore, glucosamine sulfate probably does not interfere with diabetes medications. To be cautious, if you take glucosamine sulfate and have diabetes, monitor your blood sugar closely.
    Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
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This copyrighted material is provided by Natural Medicines Comprehensive Database. Information from this source is evidence-based and objective, and without commercial influence.